Poison is always a nasty thing to deal with, as I have learned after my druid's wolf got hit with some Con draining crud.

In my experience, poison is usually expensive and of limited effectiveness. Until the GM decides to use it against the PCs, that is. Then you get things like poisons that still kill you after a neutralize poison spell is used.

Wait until you encounter magical, elemental, or, heaven forbid, infernal poison.

Magical poisons can require you to cast neutralize poison several times, due to needing to make a (difficult) check to see if you managed to remove it.

Elemental poisons are magical poisons that cause elemental damage that bypasses things like natural armor and damage resistance. Nasty stuff.

Infernal poisons are basically BAD END in a bottle. They need to be uncursed, blessed, and then neutralized. And it still might not take.

Then again, I've only seen the first one in a game I was in. Watched a game nearby that had the second and third.

Guy had his paladin commit suicide because even after they cured the infernal poison, the permanent con and str damage made him essentially 6 levels lower. At near epic levels, this is very, very bad.

Almost as bad as the Yaun-Ti poison that has auto no save death on a sucessful save or when the target is immune to poisons and turns you into a Yaun Ti NPC if you fail the save. Of Course the Paladin should have been able to afford a casting of True-Reincarnation for a completely new body with no level loss but hey one less paladin in the world so win win.

at epic levels should have just wished it better

I like the implementation of poison in the Houses of the Blooded book.

"You die."

Normal toxins don't affect the only PC race playable in that game, and the bare handful of poisons that are effective on them are rare, hard to get, illegal, and serious trouble if you get caught with them... but the book explicitly says there are no saving throws, fort checks, constitution defenses, magical aids, or anything of the like.

You get poisoned. You die.

So either the other guys is from the future or this is coming from a different timezone... I like the first idea more. also Weee here before Raxon.

How about stories about NPCs causing collateral damage?

There was a really silly NPC in a campaign I was in (same one with Hengeyokai and the succubus and idiotic clerics of Kord) that was a Gnome named Thony. He was some kind of superlinquist with a giant airship that always. ALWAYS. ended up crushing Something or another. First was a part of a castle we went to to meet an oracle. He broke some of the walls and landed on a flower bed. Later on he somehow caught one of the others when they fell off a tower. With the ship. our GM tended to ignore Falling damage in favor of plot. There was another time in my Characters hometown where we were talking to the Daimyos (cause yay Japan expy) and the cleric of Kord decided we needed Thony to help us explain stuff so he pressed the 'pick us up button'. This caused me to immediately apologize in advance before Thony broke a giant hole in the roof of the building. Thony's saga of breaking shit ended when his ship was forced to crash land... with us on it... On the moon... Side note My Brother's character ended up as a Constellation of a Velociraptor with a big dick... That was a very weird campaign.

Check again.
So, storytime. The wretched, heretical traitors who turned from the guiding light of the Immortal God-Emperor of Mankind to embrace the heresies of Chaos were holed up on the planet's main hive, with enough void shields to hold off the whole crusade fleet's orbital bombardment. The Inquisitors had a plan, though, and gave us a fuckhuge rocket with a homing beacon inside so they could drop something that could pierce the void shields.
After slogging our way through a sizable army, destroying enemy superheavy tanks and walkers while our small fry killed their small fry, we chucked the missile in (without needing any of the several rerolls we'd saved, just in case, ending one of my fumble streaks.)
THAT's when we found out they were dropping a whole damn space station on the planet's surface, with our army still in the blast zone. Our contribution to the Imperial crusading force consisting of Knight Walkers and Automata, mostly equipped with energy shielding, we saved a good 60% of the remaining troops from the wave of devastation.
And since they were Inquisitors (and one sanctioned xeno Rogue Trader) we couldn't do much more than grumble 'what a waste.' Well, after we got over how awesomely huge the explosion & shockwave were. Quoth our techpriest, "Goodbye, planetary ecosystem. We didn't like you anyway."

I technically left the first comment when my clock said 11pm (I think) on the 17th.